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p.H190R

Homo sapiens (Human)

Antibiotic Resistance

All Features

Entry O75582
gene RPS6KA5
protein name Ribosomal protein S6 kinase alpha-5
organism Homo sapiens (Human)
wt aa H
mut aa R
mutation p.H190R
effect class antibiotic_resistance
protein length 802
wt hydrophobicity -3.2
mut hydrophobicity -4.5
delta hydrophobicity -1.3
wt charge -0.0076
mut charge 0.9557
delta charge 0.9633
wt weight da 155.1546
mut weight da 174.201
delta weight da 19.0464
wt flexibility 0.95
mut flexibility 1.008
delta flexibility 0.058
wt polarity positive
mut polarity positive
polarity change 0
is charge reversal 0
mutation to proline 0
mutation to glycine 0
mutation to aromatic 0
mutation from aromatic 1
alphafold id AF-O75582-F1
pdb id 1VZO
sasa 14.445
bfactor 27.57
rna contacts 4a 0.0
protein contacts 4a 0.0
proximity to antibiotic site 45.28
nearest antibiotic linezolid
plddt 96.0
dist to dc nan
dist to ptc nan
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